Award Number : DAMD 17 - 02 - 2 - 0058 TITLE : Enhancing the Immune Response to Recombinant Plague Antigens

Among the pathogens that have been identified as potential agents of biological warfare or bioterrorism, Yersinia pestis is one of the main concerns due to the severity and potential transmissibility of the pneumonic form of the disease in humans. There are no approved vaccines for protection against pneumonic plague, but a Y. pestis-derived fusion protein (F1–V) has shown great promise as a protective antigen in murine s t h e a o p p p ©